High affinity targeting of CD23 inhibits IgE synthesis in human B cells

The low‐affinity IgE receptor FcϵRII (CD23) is part of the regulatory system controlling IgE synthesis in human B cells and exists in membrane and soluble forms. Binding of IgE to CD23 has been described to have stabilizing effects and to prevent cleavage of CD23. Previous experiments using anti‐CD2...

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Detalles Bibliográficos
Autores principales: Fellmann, Marc, Buschor, Patrick, Röthlisberger, Silvan, Zellweger, Fabian, Vogel, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693728/
https://www.ncbi.nlm.nih.gov/pubmed/26732048
http://dx.doi.org/10.1002/iid3.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693728/
https://www.ncbi.nlm.nih.gov/pubmed/26732048
http://dx.doi.org/10.1002/iid3.72

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