Organocatalytic Asymmetric Domino Michael/Henry Reaction of Indolin-3-ones with o-Formyl-β-nitrostyrenes

A highly diastereo- and enantioselective domino Michael/Henry reaction of 1-acetylindolin-3-ones with o-formyl-(E)-β-nitrostyrenes catalyzed by low loading of a quinine-derived amine-squaramide provides the corresponding indolin-3-one derivatives bearing four adjacent stereogenic centers in good to...

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Detalles Bibliográficos
Autores principales: Mahajan, Suruchi, Chauhan, Pankaj, Loh, Charles C. J., Uzungelis, Server, Raabe, Gerhard, Enders, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693955/
https://www.ncbi.nlm.nih.gov/pubmed/26722133
http://dx.doi.org/10.1055/s-0034-1379943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693955/
https://www.ncbi.nlm.nih.gov/pubmed/26722133
http://dx.doi.org/10.1055/s-0034-1379943

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