Cargando…

Organocatalytic Asymmetric Domino Michael/Henry Reaction of Indolin-3-ones with o-Formyl-β-nitrostyrenes

A highly diastereo- and enantioselective domino Michael/Henry reaction of 1-acetylindolin-3-ones with o-formyl-(E)-β-nitrostyrenes catalyzed by low loading of a quinine-derived amine-squaramide provides the corresponding indolin-3-one derivatives bearing four adjacent stereogenic centers in good to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mahajan, Suruchi, Chauhan, Pankaj, Loh, Charles C. J., Uzungelis, Server, Raabe, Gerhard, Enders, Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693955/ https://www.ncbi.nlm.nih.gov/pubmed/26722133 http://dx.doi.org/10.1055/s-0034-1379943

Ejemplares similares

Asymmetric Synthesis of Tetrahydropyridines via an Organocatalytic One-Pot Multicomponent Michael/Aza-Henry/Cyclization Triple Domino Reaction
por: Blümel, Marcus, et al.
Publicado: (2014)

Asymmetric Synthesis of Fully Substituted Cyclopentane-Oxindoles through an Organocatalytic Triple Michael Domino Reaction
por: Zou, Liang-Hua, et al.
Publicado: (2015)

Asymmetric synthesis of functionalized cyclohexanes bearing five stereocenters via a one-pot organocatalytic Michael–Michael–1,2-addition sequence
por: Chauhan, Pankaj, et al.
Publicado: (2014)

An Asymmetric Organocatalytic Quadruple Domino Reaction Employing a Vinylogous Friedel–Crafts/Michael/Michael/Aldol Condensation Sequence
por: Philipps, Arne R., et al.
Publicado: (2015)

Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
por: Jiang, Zhen-Yu, et al.
Publicado: (2010)

Asymmetric synthesis of polysubstituted chiral chromans via an organocatalytic oxa-Michael-nitro-Michael domino reaction
por: Tang, Cheng-Ke, et al.
Publicado: (2018)

Organocatalytic one-pot 1,4-/1,6-/1,2-addition sequence for the stereocontrolled formation of six consecutive stereocenters
por: Chauhan, Pankaj, et al.
Publicado: (2015)

Organocatalytic Asymmetric Synthesis of Dihydroisoquinolinones via a One-Pot Aza-Henry–Hemiaminalization–Oxidation Sequence
por: Hahn, Robert, et al.
Publicado: (2015)

Stereoselective Synthesis of Spiro-Decalin Oxindole Derivatives via Sequential Organocatalytic Michael–Domino Michael/Aldol Reaction
por: Straminelli, Leonardo, et al.
Publicado: (2022)

Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction
por: Shu, Tao, et al.
Publicado: (2016)

Asymmetric Synthesis of Substituted Thiolanes through Domino Thia-Michael–Henry Dynamic Covalent Systemic Resolution using Lipase Catalysis
por: Zhang, Yan, et al.
Publicado: (2014)

Recent advances in organocatalytic asymmetric aza-Michael reactions of amines and amides
por: Sharma, Pratibha, et al.
Publicado: (2021)

DoE‐Driven Development of an Organocatalytic Enantioselective Addition of Acetaldehyde to Nitrostyrenes in Water
por: Nori, Valeria, et al.
Publicado: (2022)

Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids
por: Hazra, Gurupada, et al.
Publicado: (2017)

Asymmetric organocatalytic Michael addition of cyclopentane-1,2-dione to alkylidene oxindole
por: Silm, Estelle, et al.
Publicado: (2022)

Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone
por: Yu, Jin-Sheng, et al.
Publicado: (2012)

Stereodivergent Organocatalytic Intramolecular Michael Addition/Lactonization for the Asymmetric Synthesis of Substituted Dihydrobenzofurans and Tetrahydrofurans
por: Belmessieri, Dorine, et al.
Publicado: (2014)

Concerted Catalysis by Nanocellulose and Proline in Organocatalytic Michael Additions
por: Ranaivoarimanana, Naliharifetra Jessica, et al.
Publicado: (2019)

Asymmetric total synthesis of smyrindiol employing an organocatalytic aldol key step
por: Enders, Dieter, et al.
Publicado: (2012)

Asymmetric Synthesis of Spirocyclopentane Oxindoles Containing Four Consecutive Stereocenters and Quaternary α-Nitro Esters via Organocatalytic Enantioselective Michael–Michael Cascade Reactions
por: Chaudhari, Prakash D., et al.
Publicado: (2019)

Organocatalytic asymmetric Michael/acyl transfer reaction between α-nitroketones and 4-arylidenepyrrolidine-2,3-diones
por: Parida, Chandrakanta, et al.
Publicado: (2021)

Organocatalytic Enantioselective Michael Reaction of Aminomaleimides with Nitroolefins Catalyzed by Takemoto’s Catalyst
por: Mu, Hongwen, et al.
Publicado: (2022)

Combining Silver Catalysis and Organocatalysis: A Sequential Michael Addition/Hydroalkoxylation One-Pot Approach to Annulated Coumarins
por: Hack, Daniel, et al.
Publicado: (2014)

Organocatalytic asymmetric chlorinative dearomatization of naphthols
por: Yin, Qin, et al.
Publicado: (2015)

Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses
por: Khong, San N., et al.
Publicado: (2012)

Regioselective α-addition of vinylogous α-ketoester enolate in organocatalytic asymmetric Michael reactions: enantioselective synthesis of Rauhut–Currier type products
por: Weng, Zhibing, et al.
Publicado: (2022)

Denitrative Cross-Couplings of Nitrostyrenes
por: Marčeková, Michaela, et al.
Publicado: (2020)

Tri(n-butyl)phosphine-promoted domino reaction for the efficient construction of spiro[cyclohexane-1,3'-indolines] and spiro[indoline-3,2'-furan-3',3''-indolines]
por: Zheng, Hui, et al.
Publicado: (2022)

Organocatalytic asymmetric synthesis of P-stereogenic molecules
por: Liu, Junyang, et al.
Publicado: (2023)

Construction of highly enantioenriched spirocyclopentaneoxindoles containing four consecutive stereocenters via thiourea-catalyzed asymmetric Michael–Henry cascade reactions
por: Du, Yonglei, et al.
Publicado: (2017)

Organocatalytic asymmetric Henry reaction of 1H-pyrrole-2,3-diones with bifunctional amine-thiourea catalysts bearing multiple hydrogen-bond donors
por: Zhang, Ming-Liang, et al.
Publicado: (2016)

Asymmetric Cascade Aza-Henry/Lactamization Reaction in the Highly Enantioselective Organocatalytic Synthesis of 3-(Nitromethyl)isoindolin-1-ones from α-Amido Sulfones
por: Serusi, Lorenzo, et al.
Publicado: (2022)

Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction
por: Ni, Qijian, et al.
Publicado: (2015)

Towards an asymmetric organocatalytic α-cyanation of β-ketoesters
por: Chowdhury, Raghunath, et al.
Publicado: (2015)

Towards an Asymmetric Organocatalytic α-Azidation of β-Ketoesters
por: Tiffner, Maximilian, et al.
Publicado: (2018)

Organocatalytic Asymmetric Synthesis of Si-Stereogenic Silyl Ethers
por: Zhou, Hui, et al.
Publicado: (2022)

Organocatalytic chiral polymeric nanoparticles for asymmetric aldol reaction
por: Abuaf, Meir, et al.
Publicado: (2023)

Kinetics Studies on a Multicomponent Knoevenagel−Michael Domino Reaction by an Automated Flow Reactor
por: Haas, Christian P., et al.
Publicado: (2019)

Enantioselective Desymmetrization of Prochiral Cyclohexanones by Organocatalytic Intramolecular Michael Additions to α,β-Unsaturated Esters**
por: Gammack Yamagata, Adam D, et al.
Publicado: (2015)

Kinetic resolution of indolines by asymmetric hydroxylamine formation
por: Wang, Gang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gvvou747du4op57g08c8v0kbkk