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The Use of Flow Cytometry to Assess the State of Chromatin in T Cells

During a proper immune response, quiescent T cells become activated upon antigen presentation to their antigen-specific T cell receptor. This leads to clonal proliferation of only those T cells that bear a receptor that recognizes the antigen. Chromatin decondensation is a hallmark of T cell activat...

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Detalles Bibliográficos
Autores principales: Bingham, Kellie N., Lee, Megan D., Rawlings, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694037/
https://www.ncbi.nlm.nih.gov/pubmed/26709948
http://dx.doi.org/10.3791/53533