OTX2 regulates the expression of TAp63 leading to macular and cochlear neuroepithelium development

OTX proteins, homologs of the Drosophila orthodenticle (Otd), are important for the morphogenesis of the neuroectoderm, and for the central nervous system formation. OTX1 and OTX2 are important for the cochlea and macula development, indeed when OTX1 is knocked down, these organs undergo development...

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Detalles Bibliográficos
Autores principales: Palombo, Ramona, Porta, Giovanni, Bruno, Ernesto, Provero, Paolo, Serra, Valeria, Neduri, Karthik, Viziano, Andrea, Alessandrini, Marco, Micarelli, Alessandro, Ottaviani, Fabrizio, Melino, Gerry, Terrinoni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694063/
https://www.ncbi.nlm.nih.gov/pubmed/26554466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694063/
https://www.ncbi.nlm.nih.gov/pubmed/26554466

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