Loss of membrane‐bound lytic transglycosylases increases outer membrane permeability and β‐lactam sensitivity in Pseudomonas aeruginosa

The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial infections. Its relatively impermeable outer membrane (OM) limits antibiotic entry, and a chromosomally encoded AmpC β‐lactamase inactivates β‐lactam antibiotics. AmpC expression is linked to peptidoglycan (PG) recycl...

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Detalles Bibliográficos
Autores principales: Lamers, Ryan P., Nguyen, Uyen T., Nguyen, Ylan, Buensuceso, Ryan N. C., Burrows, Lori L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694138/
https://www.ncbi.nlm.nih.gov/pubmed/26374494
http://dx.doi.org/10.1002/mbo3.286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694138/
https://www.ncbi.nlm.nih.gov/pubmed/26374494
http://dx.doi.org/10.1002/mbo3.286

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