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Loss of membrane‐bound lytic transglycosylases increases outer membrane permeability and β‐lactam sensitivity in Pseudomonas aeruginosa
The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial infections. Its relatively impermeable outer membrane (OM) limits antibiotic entry, and a chromosomally encoded AmpC β‐lactamase inactivates β‐lactam antibiotics. AmpC expression is linked to peptidoglycan (PG) recycl...
Autores principales: | Lamers, Ryan P., Nguyen, Uyen T., Nguyen, Ylan, Buensuceso, Ryan N. C., Burrows, Lori L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694138/ https://www.ncbi.nlm.nih.gov/pubmed/26374494 http://dx.doi.org/10.1002/mbo3.286 |
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