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Characterization of Mycobacterium smegmatis sigF mutant and its regulon: overexpression of SigF antagonist (MSMEG_1803) in M. smegmatis mimics sigF mutant phenotype, loss of pigmentation, and sensitivity to oxidative stress

In Mycobacterium smegmatis, sigF is widely expressed during different growth stages and plays role in adaptation to stationary phase and oxidative stress. Using a sigF deletion mutant of M. smegmatis mc(2)155, we demonstrate that SigF is not essential for growth of bacterium. Deletion of sigF result...

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Detalles Bibliográficos
Autores principales: Singh, Anirudh K., Dutta, Debashis, Singh, Vandana, Srivastava, Vishal, Biswas, Rajesh K., Singh, Bhupendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694148/
https://www.ncbi.nlm.nih.gov/pubmed/26434659
http://dx.doi.org/10.1002/mbo3.288