Cargando…

Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload

Atrial remodeling due to elevated arterial pressure predisposes the heart to atrial fibrillation (AF). Although abnormal sarcoplasmic reticulum (SR) function has been associated with AF, there is little information on the effects of elevated afterload on atrial Ca(2+)-handling. We investigated the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Haifei, Cannell, Mark B., Kim, Shang Jin, Watson, Judy J., Norman, Ruth, Calaghan, Sarah C., Orchard, Clive H., James, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694654/
https://www.ncbi.nlm.nih.gov/pubmed/26713852
http://dx.doi.org/10.1371/journal.pone.0144309