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Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload
Atrial remodeling due to elevated arterial pressure predisposes the heart to atrial fibrillation (AF). Although abnormal sarcoplasmic reticulum (SR) function has been associated with AF, there is little information on the effects of elevated afterload on atrial Ca(2+)-handling. We investigated the e...
Autores principales: | Zhang, Haifei, Cannell, Mark B., Kim, Shang Jin, Watson, Judy J., Norman, Ruth, Calaghan, Sarah C., Orchard, Clive H., James, Andrew F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694654/ https://www.ncbi.nlm.nih.gov/pubmed/26713852 http://dx.doi.org/10.1371/journal.pone.0144309 |
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