Cigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway

BACKGROUND: Evidence suggests that suppressor of cytokine signaling 1 (SOCS1) is crucial for the negative regulation of inflammation. We investigated the relationship between smoking, SOCS1, and leukotriene B4 (LTB4) in vitro and in clinical samples of COPD; besides which we detected the impact of L...

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Detalles Bibliográficos
Autores principales: Dong, Ran, Xie, Liang, Zhao, Kaishun, Zhang, Qiurui, Zhou, Min, He, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694688/
https://www.ncbi.nlm.nih.gov/pubmed/26730186
http://dx.doi.org/10.2147/COPD.S96412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694688/
https://www.ncbi.nlm.nih.gov/pubmed/26730186
http://dx.doi.org/10.2147/COPD.S96412

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