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Cigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway
BACKGROUND: Evidence suggests that suppressor of cytokine signaling 1 (SOCS1) is crucial for the negative regulation of inflammation. We investigated the relationship between smoking, SOCS1, and leukotriene B4 (LTB4) in vitro and in clinical samples of COPD; besides which we detected the impact of L...
Autores principales: | Dong, Ran, Xie, Liang, Zhao, Kaishun, Zhang, Qiurui, Zhou, Min, He, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694688/ https://www.ncbi.nlm.nih.gov/pubmed/26730186 http://dx.doi.org/10.2147/COPD.S96412 |
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