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Combining Evolutionary Information and an Iterative Sampling Strategy for Accurate Protein Structure Prediction

Recent work has shown that the accuracy of ab initio structure prediction can be significantly improved by integrating evolutionary information in form of intra-protein residue-residue contacts. Following this seminal result, much effort is put into the improvement of contact predictions. However, t...

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Detalles Bibliográficos
Autores principales: Braun, Tatjana, Koehler Leman, Julia, Lange, Oliver F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694711/
https://www.ncbi.nlm.nih.gov/pubmed/26713437
http://dx.doi.org/10.1371/journal.pcbi.1004661