ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin

ChromoShake is a three-dimensional simulator designed to find the thermodynamically favored states for given chromosome geometries. The simulator has been applied to a geometric model based on experimentally determined positions and fluctuations of DNA and the distribution of cohesin and condensin i...

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Detalles Bibliográficos
Autores principales: Lawrimore, Josh, Aicher, Joseph K., Hahn, Patrick, Fulp, Alyona, Kompa, Ben, Vicci, Leandra, Falvo, Michael, Taylor, Russell M., Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694754/
https://www.ncbi.nlm.nih.gov/pubmed/26538024
http://dx.doi.org/10.1091/mbc.E15-08-0575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694754/
https://www.ncbi.nlm.nih.gov/pubmed/26538024
http://dx.doi.org/10.1091/mbc.E15-08-0575

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