Cargando…
ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin
ChromoShake is a three-dimensional simulator designed to find the thermodynamically favored states for given chromosome geometries. The simulator has been applied to a geometric model based on experimentally determined positions and fluctuations of DNA and the distribution of cohesin and condensin i...
Autores principales: | Lawrimore, Josh, Aicher, Joseph K., Hahn, Patrick, Fulp, Alyona, Kompa, Ben, Vicci, Leandra, Falvo, Michael, Taylor, Russell M., Bloom, Kerry |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694754/ https://www.ncbi.nlm.nih.gov/pubmed/26538024 http://dx.doi.org/10.1091/mbc.E15-08-0575 |
Ejemplares similares
-
Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring
por: Stephens, Andrew D., et al.
Publicado: (2011) -
DNA loops generate intracentromere tension in mitosis
por: Lawrimore, Josh, et al.
Publicado: (2015) -
Geometric partitioning of cohesin and condensin is a consequence of chromatin loops
por: Lawrimore, Josh, et al.
Publicado: (2018) -
Point centromeres contain more than a single centromere-specific Cse4 (CENP-A) nucleosome
por: Lawrimore, Josh, et al.
Publicado: (2011) -
Pericentric chromatin loops function as a nonlinear spring in mitotic force balance
por: Stephens, Andrew D., et al.
Publicado: (2013)