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Dissecting in vivo steady-state dynamics of karyopherin-dependent nuclear transport

Karyopherin-dependent molecular transport through the nuclear pore complex is maintained by constant recycling pathways of karyopherins coupled with the Ran-dependent cargo catch-and-release mechanism. Although many studies have revealed the bidirectional dynamics of karyopherins, the entire kinetic...

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Detalles Bibliográficos
Autores principales: Lolodi, Ogheneochukome, Yamazaki, Hiroya, Otsuka, Shotaro, Kumeta, Masahiro, Yoshimura, Shige H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694755/
https://www.ncbi.nlm.nih.gov/pubmed/26538027
http://dx.doi.org/10.1091/mbc.E15-08-0601