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Lamin B1 protein is required for dendrite development in primary mouse cortical neurons

Lamin B1, a key component of the nuclear lamina, plays an important role in brain development and function. A duplication of the human lamin B1 (LMNB1) gene has been linked to adult-onset autosomal dominant leukodystrophy, and mouse and human loss-of-function mutations in lamin B1 are susceptibility...

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Detalles Bibliográficos
Autores principales: Giacomini, Caterina, Mahajani, Sameehan, Ruffilli, Roberta, Marotta, Roberto, Gasparini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694760/
https://www.ncbi.nlm.nih.gov/pubmed/26510501
http://dx.doi.org/10.1091/mbc.E15-05-0307