A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis

Insulin promotes glucose uptake into skeletal muscle through recruitment of glucose transporter 4 (GLUT4) to the plasma membrane. Rab GTPases are molecular switches mobilizing intracellular vesicles, and Rab13 is necessary for insulin-regulated GLUT4–vesicle exocytic translocation in muscle cells. W...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Jaldin-Fincati, Javier, Liu, Zhi, Bilan, Philip J., Klip, Amira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694764/
https://www.ncbi.nlm.nih.gov/pubmed/26538022
http://dx.doi.org/10.1091/mbc.E15-05-0319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694764/
https://www.ncbi.nlm.nih.gov/pubmed/26538022
http://dx.doi.org/10.1091/mbc.E15-05-0319

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