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A complex of Rab13 with MICAL-L2 and α-actinin-4 is essential for insulin-dependent GLUT4 exocytosis
Insulin promotes glucose uptake into skeletal muscle through recruitment of glucose transporter 4 (GLUT4) to the plasma membrane. Rab GTPases are molecular switches mobilizing intracellular vesicles, and Rab13 is necessary for insulin-regulated GLUT4–vesicle exocytic translocation in muscle cells. W...
Autores principales: | Sun, Yi, Jaldin-Fincati, Javier, Liu, Zhi, Bilan, Philip J., Klip, Amira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694764/ https://www.ncbi.nlm.nih.gov/pubmed/26538022 http://dx.doi.org/10.1091/mbc.E15-05-0319 |
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