OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates

Mutation of the inositol 5-phosphatase OCRL1 causes Lowe syndrome and Dent-2 disease. Loss of OCRL1 function perturbs several cellular processes, including membrane traffic, but the underlying mechanisms remain poorly defined. Here we show that OCRL1 is part of the membrane-trafficking machinery ope...

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Detalles Bibliográficos
Autores principales: Billcliff, Peter G., Noakes, Christopher J., Mehta, Zenobia B., Yan, Guanhua, Mak, LokHang, Woscholski, Rudiger, Lowe, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694765/
https://www.ncbi.nlm.nih.gov/pubmed/26510499
http://dx.doi.org/10.1091/mbc.E15-06-0329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694765/
https://www.ncbi.nlm.nih.gov/pubmed/26510499
http://dx.doi.org/10.1091/mbc.E15-06-0329

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