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Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo

The tumor suppressor p53 is a transcription factor that coordinates the cellular response to DNA damage. Here we provide an integrated analysis of p53 genomic occupancy and p53-dependent gene regulation in the splenic B and non-B cell compartments of mice exposed to whole-body ionizing radiation, pr...

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Detalles Bibliográficos
Autores principales: Tonelli, Claudia, Morelli, Marco J., Bianchi, Salvatore, Rotta, Luca, Capra, Thelma, Sabò, Arianna, Campaner, Stefano, Amati, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694782/
https://www.ncbi.nlm.nih.gov/pubmed/26372730