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Age-related somatic mutations in the cancer genome

Aging is associated with an increased risk of cancer, possibly in part because of an age-related increase in mutations in normal tissues. Due to their extremely low abundance, somatic mutations in normal tissues frequently escape detection. Tumors, as clonal expansions of single cells, can provide i...

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Detalles Bibliográficos
Autores principales: Milholland, Brandon, Auton, Adam, Suh, Yousin, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694783/
https://www.ncbi.nlm.nih.gov/pubmed/26384365