A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing

Chimeric antigen receptor (CAR)-expressing T cells are a promising therapeutic option for patients with cancer. We developed a new CAR directed against the disialoganglioside GD2, a surface molecule expressed in neuroblastoma and in other neuroectoderm-derived neoplasms. The anti-GD2 single-chain va...

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Detalles Bibliográficos
Autores principales: Prapa, Malvina, Caldrer, Sara, Spano, Carlotta, Bestagno, Marco, Golinelli, Giulia, Grisendi, Giulia, Petrachi, Tiziana, Conte, Pierfranco, Horwitz, Edwin M., Campana, Dario, Paolucci, Paolo, Dominici, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694800/
https://www.ncbi.nlm.nih.gov/pubmed/26298772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694800/
https://www.ncbi.nlm.nih.gov/pubmed/26298772

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