Individualized strategies to target specific mechanisms of disease in malignant melanoma patients displaying unique mutational signatures

Targeted treatment of advanced melanoma could benefit from the precise molecular characterization of melanoma samples. Using a melanoma-specific selection of 217 genes, we performed targeted deep sequencing of a series of biopsies, from advanced melanoma cases, with a Breslow index of ≥4 mm, and/or...

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Detalles Bibliográficos
Autores principales: Curiel-Olmo, Soraya, García-Castaño, Almudena, Vidal, Rebeca, Pisonero, Helena, Varela, Ignacio, León-Castillo, Alicia, Trillo, Eugenio, González-Vela, Carmen, García-Diaz, Nuria, Almaraz, Carmen, Moreno, Thaidy, Cereceda, Laura, Madureira, Rebeca, Martinez, Nerea, Ortiz-Romero, Pablo, Valdizán, Elsa, Piris, Miguel, Vaqué, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694844/
https://www.ncbi.nlm.nih.gov/pubmed/26327537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694844/
https://www.ncbi.nlm.nih.gov/pubmed/26327537

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