Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK

Hemangioma is a benign vascular neoplasm of unknown etiology. In this study, we generated an endothelial-specific PyMT gene-expressing transgenic mouse model that spontaneously develops hemangioma. Based on this transgenic model, a specific binding between PyMT and the core AC dimer of protein phosp...

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Detalles Bibliográficos
Autores principales: Xie, Furong, Bao, Xin, Yu, Jingshuang, Chen, Wantao, Wang, Lizhen, Zhang, Zhiyuan, Xu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694857/
https://www.ncbi.nlm.nih.gov/pubmed/26308070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694857/
https://www.ncbi.nlm.nih.gov/pubmed/26308070

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