TNF signaling mediates an enzalutamide-induced metastatic phenotype of prostate cancer and microenvironment cell co-cultures

The dramatic responses tumors display to targeted therapies are limited by acquired or pre-existing mechanisms of therapy resistance. We recently discovered that androgen receptor blockade by the anti-androgen enzalutamide paradoxically enhanced metastasis and that these pro-metastatic effects were...

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Detalles Bibliográficos
Autores principales: Sha, Kai, Yeh, Shuyuan, Chang, Chawnshang, Nastiuk, Kent L., Krolewski, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694862/
https://www.ncbi.nlm.nih.gov/pubmed/26327448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694862/
https://www.ncbi.nlm.nih.gov/pubmed/26327448

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