Survival of primary, but not of cancer cells after combined Plk1-HDAC inhibition

In the current study we examined the combination of SAHA and SBE13 in cancer and non-cancer cells. HeLa cells displayed a synergistically reduced cell proliferation, which was much weaker in hTERT-RPE1 or NIH-3T3 cells. Cell cycle distribution differed in HeLa, hTERT-RPE1 and NIH-3T3 cells. SAHA-tre...

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Detalles Bibliográficos
Autores principales: Lange, Lisa, Hemmerich, Peter, Spänkuch, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694867/
https://www.ncbi.nlm.nih.gov/pubmed/26317649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694867/
https://www.ncbi.nlm.nih.gov/pubmed/26317649

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