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GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK/FOXO3a pathway

GL-V9, a new synthesized flavonoid derivative, has been reported to possess anti-cancer properties in our previous studies. Uncontrolled overproduction of reactive oxygen species (ROS) has been implicated in oxidative damage of inflammatory bowel disease (IBD). In this study, we aimed to investigate...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Sun, Yang, Ding, Youxiang, Wang, Xiaoping, Zhou, Yuxin, Li, Wenjun, Huang, Shaoliang, Li, Zhiyu, Kong, Lingyi, Guo, Qinglong, Lu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694902/
https://www.ncbi.nlm.nih.gov/pubmed/26327408