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GL-V9, a new synthetic flavonoid derivative, ameliorates DSS-induced colitis against oxidative stress by up-regulating Trx-1 expression via activation of AMPK/FOXO3a pathway
GL-V9, a new synthesized flavonoid derivative, has been reported to possess anti-cancer properties in our previous studies. Uncontrolled overproduction of reactive oxygen species (ROS) has been implicated in oxidative damage of inflammatory bowel disease (IBD). In this study, we aimed to investigate...
Autores principales: | Zhao, Yue, Sun, Yang, Ding, Youxiang, Wang, Xiaoping, Zhou, Yuxin, Li, Wenjun, Huang, Shaoliang, Li, Zhiyu, Kong, Lingyi, Guo, Qinglong, Lu, Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694902/ https://www.ncbi.nlm.nih.gov/pubmed/26327408 |
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