An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy

Recent studies have shown that MMP-14 is highly expressed in a panel of human solid tumors and poses as a potential molecular target for anticancer drugs. Currently, major strategies for targeted therapeutics have mainly focused on the use of antibody or ligand-based agents. For seeking an alternati...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Liu, Xiu-Jun, Li, Liang, Zhang, Sheng-Hua, Li, Yi, Gao, Rui-Juan, Zhen, Yong-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694904/
https://www.ncbi.nlm.nih.gov/pubmed/26314845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694904/
https://www.ncbi.nlm.nih.gov/pubmed/26314845

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