MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1

The mechanism of cisplatin resistance in ovarian cancer is not clearly understood. In the present investigation, we found that the expression levels of miR-497 were reduced in chemotherapy-resistant ovarian cancer cells and tumor tissues due to hypermethylation of miR-497 promoter. Low miR-497 expre...

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Detalles Bibliográficos
Autores principales: Xu, Shaohua, Fu, Guang-Bo, Tao, Zhen, OuYang, Jun, Kong, Fanfei, Jiang, Bing-Hua, Wan, Xiaoping, Chen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694914/
https://www.ncbi.nlm.nih.gov/pubmed/26238185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694914/
https://www.ncbi.nlm.nih.gov/pubmed/26238185

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