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MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1

The mechanism of cisplatin resistance in ovarian cancer is not clearly understood. In the present investigation, we found that the expression levels of miR-497 were reduced in chemotherapy-resistant ovarian cancer cells and tumor tissues due to hypermethylation of miR-497 promoter. Low miR-497 expre...

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Detalles Bibliográficos
Autores principales:	Xu, Shaohua, Fu, Guang-Bo, Tao, Zhen, OuYang, Jun, Kong, Fanfei, Jiang, Bing-Hua, Wan, Xiaoping, Chen, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694914/ https://www.ncbi.nlm.nih.gov/pubmed/26238185

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