Liver X Receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization

Increasing evidence indicates that Liver X Receptors (LXRs) have some anticancer properties. We recently demonstrated that LXR ligands induce colon cancer cell pyroptosis through an LXRβ-dependent pathway. In the present study, we showed that human colon cancer cell lines presented differential cyto...

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Detalles Bibliográficos
Autores principales: Courtaut, Flavie, Derangère, Valentin, Chevriaux, Angélique, Ladoire, Sylvain, Cotte, Alexia K., Arnould, Laurent, Boidot, Romain, Rialland, Mickaël, Ghiringhelli, François, Rébé, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694942/
https://www.ncbi.nlm.nih.gov/pubmed/26450852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694942/
https://www.ncbi.nlm.nih.gov/pubmed/26450852

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