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A core of kinase-regulated interactomes defines the neoplastic MDSC lineage

Myeloid-derived suppressor cells (MDSCs) differentiate from bone marrow precursors, expand in cancer-bearing hosts and accelerate tumor progression. MDSCs have become attractive therapeutic targets, as their elimination strongly enhances anti-neoplastic treatments. Here, immature myeloid dendritic c...

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Detalles Bibliográficos
Autores principales: Gato-Cañas, Maria, de Morentin, Xabier Martinez, Blanco-Luquin, Idoia, Fernandez-Irigoyen, Joaquin, Zudaire, Isabel, Liechtenstein, Therese, Arasanz, Hugo, Lozano, Teresa, Casares, Noelia, Chaikuad, Apirat, Knapp, Stefan, Guerrero-Setas, David, Escors, David, Kochan, Grazyna, Santamaría, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694980/
https://www.ncbi.nlm.nih.gov/pubmed/26320174