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Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme

Glioblastoma multiforme (GBM) possesses florid angiogenesis. However, the anti-angiogenic agent, Bevacizumab, did not improve overall survival of GBM patients. For more durable anti-angiogenic treatment, we interrogated resistant mechanisms of GBM against Bevacizumab. Serial orthotopic transplantati...

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Detalles Bibliográficos
Autores principales: Kang, Wonyoung, Kim, Sung Heon, Cho, Hee Jin, Jin, Juyoun, Lee, Jeongwu, Joo, Kyeung Min, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694986/
https://www.ncbi.nlm.nih.gov/pubmed/26336988