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Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression

The FOXM1 transcription factor network is frequently activated in high-grade serous ovarian cancer (HGSOC), the most common and lethal subtype of epithelial ovarian cancer (EOC). We used primary human EOC tissues, HGSOC cell lines, mouse and human ovarian surface epithelial (OSE) cells, and a murine...

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Detalles Bibliográficos
Autores principales: Barger, Carter J., Zhang, Wa, Hillman, Joanna, Stablewski, Aimee B., Higgins, Michael J., Vanderhyden, Barbara C., Odunsi, Kunle, Karpf, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695012/
https://www.ncbi.nlm.nih.gov/pubmed/26243836