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Crocetinic acid inhibits hedgehog signaling to inhibit pancreatic cancer stem cells

Pancreatic cancer is the fourth leading cause of cancer deaths in the US and no significant treatment is currently available. Here, we describe the effect of crocetinic acid, which we purified from commercial saffron compound crocetin using high performance liquid chromatography. Crocetinic acid inh...

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Detalles Bibliográficos
Autores principales: Rangarajan, Parthasarathy, Subramaniam, Dharmalingam, Paul, Santanu, Kwatra, Deep, Palaniyandi, Kanagaraj, Islam, Shamima, Harihar, Sitaram, Ramalingam, Satish, Gutheil, William, Putty, Sandeep, Pradhan, Rohan, Padhye, Subhash, Welch, Danny R., Anant, Shrikant, Dhar, Animesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695016/
https://www.ncbi.nlm.nih.gov/pubmed/26317547