Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial-to-mesenchymal transition in colon and breast cancers

The Nef-M1 peptide competes effectively with the natural ligand of CXC chemokine receptor 4 (CXCR4), stromal cell-derived factor 1-alpha, to induce apoptosis and inhibit growth in colon cancer (CRC) and breast cancer (BC). Its role in tumor angiogenesis, and epithelial-to-mesenchymal transition (EMT...

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Detalles Bibliográficos
Autores principales: Katkoori, Venkat R., Basson, Marc D., Bond, Vincent C., Manne, Upender, Bumpers, Harvey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695024/
https://www.ncbi.nlm.nih.gov/pubmed/26318034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695024/
https://www.ncbi.nlm.nih.gov/pubmed/26318034

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