LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2

Long non-coding RNA HOTAIR predicts negative tumor prognosis and exhibits oncogenic activity. Herein, we demonstrate HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2. Mechanistically, HOTAIR reduces the recuritment of the CREB, P300, RNA polII onto the SE...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, An, Jiahui, Wu, Mengying, Zheng, Qidi, Gui, Xin, Li, Tianming, Pu, Hu, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695030/
https://www.ncbi.nlm.nih.gov/pubmed/26172293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695030/
https://www.ncbi.nlm.nih.gov/pubmed/26172293

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