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USP35 activated by miR let-7a inhibits cell proliferation and NF-κB activation through stabilization of ABIN-2

Ubiquitin specific protease 35 (USP35) is a member of deubiquitylases (DUBs). It remains largely unknown about the biological role and the regulation mechanism of USP35. Here, we first identified miR let-7a as a positive regulator of USP35 expression and showed that USP35 expression positively corre...

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Detalles Bibliográficos
Autores principales: Liu, Chunyan, Wang, Lina, Chen, Weiwen, Zhao, Shihu, Yin, Chunli, Lin, Yani, Jiang, Anli, Zhang, Pengju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695033/
https://www.ncbi.nlm.nih.gov/pubmed/26348204