RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells

Intratumoral heterogeneity and treatment resistance drive breast cancer (BC) metastasis and recurrence. The RUNX2 transcription factor is upregulated in early stage luminal BC. However, the precise mechanism by which RUNX2 regulates an oncogenic phenotype in luminal BCs remains an enigma. We show th...

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Detalles Bibliográficos
Autores principales: Brusgard, Jessica L., Choe, Moran, Chumsri, Saranya, Renoud, Keli, MacKerell, Alexander D., Sudol, Marius, Passaniti, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695049/
https://www.ncbi.nlm.nih.gov/pubmed/26320173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695049/
https://www.ncbi.nlm.nih.gov/pubmed/26320173

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