Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16(INK4a) deficiency and telomere-dependent genotoxic stress

Virtually all human cancers display chromosome instability (CIN), a condition in which chromosomes are gained or lost at a high rate. CIN occurs early in cancer development where it may undermine the advance of the neoplastic disease. With the aim of establishing the mechanisms underlying CIN in can...

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Detalles Bibliográficos
Autores principales: Domínguez, Daniel, Feijoo, Purificación, Bernal, Aina, Ercilla, Amaia, Agell, Neus, Genescà, Anna, Tusell, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695057/
https://www.ncbi.nlm.nih.gov/pubmed/26318587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695057/
https://www.ncbi.nlm.nih.gov/pubmed/26318587

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