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Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16(INK4a) deficiency and telomere-dependent genotoxic stress
Virtually all human cancers display chromosome instability (CIN), a condition in which chromosomes are gained or lost at a high rate. CIN occurs early in cancer development where it may undermine the advance of the neoplastic disease. With the aim of establishing the mechanisms underlying CIN in can...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695057/ https://www.ncbi.nlm.nih.gov/pubmed/26318587 |