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Therapeutic efficacy of combined BRAF and MEK inhibition in metastatic melanoma: a comprehensive network meta-analysis of randomized controlled trials

BACKGROUND: Several recent randomized clinical trials have preliminarily demonstrated that initial targeted therapy with combined BRAF and MEK inhibition is more effective in metastatic melanoma (MM) than single agent. To guide therapeutic decisions, we did a comprehensive network meta-analysis to i...

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Detalles Bibliográficos
Autores principales: Mai, Ruiqin, Zhou, Songxia, Zhong, Weixiang, Rong, Siming, Cong, Zhichao, Li, Yunxian, Xie, Qizhi, Chen, Huanming, Li, Xiaoyun, Liu, Shuhui, Cheng, Yabin, Huang, Yuanshen, Zhou, Youwen, Zhang, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695075/
https://www.ncbi.nlm.nih.gov/pubmed/26143635