The Immunodominance Change and Protection of CD4(+) T-Cell Responses Elicited by an Envelope Protein Domain III-Based Tetravalent Dengue Vaccine in Mice

Dengue is the leading cause of mosquito-borne viral infections and no vaccine is available now. Envelope protein domain III (ED3) is the major target for the binding of dengue virus neutralizing antibodies; however, the ED3-specifc T-cell response is less well understood. To investigate the T-cell r...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hsin-Wei, Hu, Hui-Mei, Wu, Szu-Hsien, Chiang, Chen-Yi, Hsiao, Yu-Ju, Wu, Chia-Kai, Hsieh, Chun-Hsiang, Chung, Han-Hsuan, Chong, Pele, Leng, Chih-Hsiang, Pan, Chien-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695087/
https://www.ncbi.nlm.nih.gov/pubmed/26714037
http://dx.doi.org/10.1371/journal.pone.0145717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695087/
https://www.ncbi.nlm.nih.gov/pubmed/26714037
http://dx.doi.org/10.1371/journal.pone.0145717

Ejemplares similares