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A Boolean Function for Neural Induction Reveals a Critical Role of Direct Intercellular Interactions in Patterning the Ectoderm of the Ascidian Embryo

A complex system of multiple signaling molecules often produce differential gene expression patterns in animal embryos. In the ascidian embryo, four signaling ligands, Ephrin-A.d (Efna.d), Fgf9/16/20, Admp, and Gdf1/3-r, coordinately induce Otx expression in the neural lineage at the 32-cell stage....

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Detalles Bibliográficos
Autores principales: Ohta, Naoyuki, Waki, Kana, Mochizuki, Atsushi, Satou, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695095/
https://www.ncbi.nlm.nih.gov/pubmed/26714026
http://dx.doi.org/10.1371/journal.pcbi.1004687