Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma

Dysregulated NF-κB signaling is critical for lymphomagenesis. The regulation, function, and clinical relevance of c-Rel/NF-κB activation in diffuse large B-cell lymphoma (DLBCL) have not been well studied. In this study we analyzed the prognostic significance and gene-expression signature of c-Rel n...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ling, Xu-Monette, Zijun Y., Ok, Chi Young, Tzankov, Alexandar, Manyam, Ganiraju C., Sun, Ruifan, Visco, Carlo, Zhang, Mingzhi, Montes-Moreno, Santiago, Dybkaer, Karen, Chiu, April, Orazi, Attilio, Zu, Youli, Bhagat, Govind, Richards, Kristy L., Hsi, Eric D., Choi, William W.L., van Krieken, J. Han, Huh, Jooryung, Ponzoni, Maurilio, Ferreri, Andrés J.M., Møller, Michael B., Wang, Jinfeng, Parsons, Ben M., Winter, Jane N., Piris, Miguel A., Pham, Lan V., Medeiros, L. Jeffrey, Young, Ken H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695110/
https://www.ncbi.nlm.nih.gov/pubmed/26324762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695110/
https://www.ncbi.nlm.nih.gov/pubmed/26324762

Ejemplares similares