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Quantifying signaling pathway activation to monitor the quality of induced pluripotent stem cells

Many attempts have been made to evaluate the safety and potency of human induced pluripotent stem cells (iPSCs) for clinical applications using transcriptome data, but results so far have been ambiguous or even contradictory. Here, we characterized stem cells at the pathway level, rather than at the...

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Detalles Bibliográficos
Autores principales: Makarev, Eugene, Fortney, Kristen, Litovchenko, Maria, Braunewell, Karl H., Zhavoronkov, Alex, Atala, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695112/
https://www.ncbi.nlm.nih.gov/pubmed/26327604