Cargando…
Quantifying signaling pathway activation to monitor the quality of induced pluripotent stem cells
Many attempts have been made to evaluate the safety and potency of human induced pluripotent stem cells (iPSCs) for clinical applications using transcriptome data, but results so far have been ambiguous or even contradictory. Here, we characterized stem cells at the pathway level, rather than at the...
Autores principales: | Makarev, Eugene, Fortney, Kristen, Litovchenko, Maria, Braunewell, Karl H., Zhavoronkov, Alex, Atala, Anthony |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695112/ https://www.ncbi.nlm.nih.gov/pubmed/26327604 |
Ejemplares similares
-
Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity
por: Danilov, Anton, et al.
Publicado: (2015) -
c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells
por: Chen, Pei-Min, et al.
Publicado: (2015) -
TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis
por: Li, Guihua, et al.
Publicado: (2016) -
Drosophila PEBP1 inhibits intestinal stem cell aging via suppression of ERK pathway
por: Pyo, Jung-Hoon, et al.
Publicado: (2018) -
DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)