Extracellularly secreted APE1/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation

The present study evaluated the mechanism of apoptosis caused by post-translational modification, hyperacetylation in triple-negative breast cancer (TNBC) cells. We previously showed that trichostatin A (TSA) induced secretion of acetylated apurinic apyrimidinic endonuclease 1/redox factor-1 (Ac-APE...

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Detalles Bibliográficos
Autores principales: Lee, Yu Ran, Kim, Ki Mo, Jeon, Byeong Hwa, Choi, Sunga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695125/
https://www.ncbi.nlm.nih.gov/pubmed/26125438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695125/
https://www.ncbi.nlm.nih.gov/pubmed/26125438

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